Summary of FASLG

This gene encodes a protein that is important for immune system regulation and DNA transcription. Mutations can cause lung cancer (R).


The Function of FASLG

The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Protein names

Recommended name:

Tumor necrosis factor ligand superfamily member 6

Short name:

APL

Alternative name(s):

Apoptosis antigen ligand
APTL
CD95 ligand
CD95-L
Fas antigen ligand
Fas ligand
FasL
CD antigen CD178
Receptor-binding FasL ectodomain
Soluble Fas ligand
sFasL
FasL ICD
SPPL2A-processed FasL form
SPA

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Top Gene-Substance Interactions

FASLG Interacts with These Diseases

Substances That Increase FASLG

Substances That Decrease FASLG

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical