The EGFR gene encodes a receptor protein called the epidermal growth factor receptor, which binds to ligands and receive signals that help the cell respond to its environment. This helps promote cell growth and division and cell survival (R). 


Isoform 2 may act as an antagonist of EGF action.

Protein names

Recommended name:

Epidermal growth factor receptor

Alternative name(s):

Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase erbB-1

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