Summary of EGFR

The EGFR gene encodes a receptor protein called the epidermal growth factor receptor, which binds to ligands and receive signals that help the cell respond to its environment. This helps promote cell growth and division and cell survival (R). 

The Function of EGFR

Isoform 2 may act as an antagonist of EGF action.

Protein names

Recommended name:

Epidermal growth factor receptor

Alternative name(s):

Proto-oncogene c-ErbB-1
Receptor tyrosine-protein kinase erbB-1

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Top Gene-Substance Interactions

EGFR Interacts with These Diseases

Substances That Increase EGFR

Substances That Decrease EGFR

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity