Summary

CYP1A2 encodes for an enzyme (cytochrome P450 family 1 subfamily A member 2) and catalyzes reactions involved in drug metabolism and synthesis of cholesterol, steroids, substances, and other lipids (R). 

It is associated with lung cancer risk because it can metabolize hydrocarbons from cigarette smoke to carcinogens (R).

Inhibitors of this enzyme include fluoroquinolones (antibiotics), bactericidal, herbs and herbal teas (R).

Inducers of the enzyme include nicotine and vegetables like broccoli or cauliflower (R). 

Caffeine, aflatoxin, carcinogens, heterocyclic amines and tylenol are metabolized by CYP1A2 in the liver.


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