Summary of CYBA

This gene encodes a protein that is subunit of a group of proteins that forms an enzyme complex called NADPH oxidase, which plays an important role in the immune system. The complex adjust the inflammatory responses (R). 


The Function of CYBA

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Protein names

Recommended name:

Cytochrome b-245 light chain

Alternative name(s):

Cytochrome b(558
Cytochrome b558 subunit alpha
Neutrophil cytochrome b 22 kDa polypeptide
Superoxide-generating NADPH oxidase light chain subunit
p22 phagocyte B-cytochrome
p22-phox
p22phox

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Top Gene-Substance Interactions

CYBA Interacts with These Diseases

Substances That Increase CYBA

Substances That Decrease CYBA

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical