Summary of CNR1

CNR1 codes for the CB1 cannabinoid receptor.

The cannabinoid system plays an important role in neural plasticity, stress response, and learning and memory (R).

CB1 receptors are found in particularly high density in regions known to play a role in emotional regulation and memory, and regions suggested to play a role in ADHD, emotional regulation, and other psychiatric disorders (e.g., bipolar, mood, anxiety disorders) (R).

The cannabinoid system is also important in dampening intestinal inflammation in humans.  It increases intestinal flow/motility (R).

CB1 receptors are found primarily in the brain and appear to impact predominately the GABA and Glutamate systems (R), but also affects the dopamine and serotonin systems.

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Protein names

Recommended name:

Cannabinoid receptor 1

Short name:


Alternative name(s):


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Top Gene-Substance Interactions

CNR1 Interacts with These Diseases


Substances That Increase CNR1

Substances That Decrease CNR1

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity