Summary of CLPTM1L
This gene encodes a membrane protein. Overexpression can cause programmed cell death while polymorphisms can increase susceptibility to cancer (R).
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The Function of CLPTM1L
Enhances cisplatin-mediated apoptosis, when overexpressed.
Protein names
Recommended name:
Cleft lip and palate transmembrane protein 1-like proteinAlternative name(s):
CLPTM1-like proteinCisplatin resistance-related protein 9
CRR9p
- RS31489 (CLPTM1L) ??
- RS31490 (CLPTM1L) ??
- RS401681 (CLPTM1L) ??
- RS402710 (CLPTM1L) ??
- RS4975616 (CLPTM1L) ??
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Top Gene-Substance Interactions
CLPTM1L Interacts with These Diseases
| Disease | Score |
Substances That Increase CLPTM1L
| Substances | Interaction | Organism | Category |
Substances That Decrease CLPTM1L
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Induction:
Up-regulated by cisplatin.