Summary of CHAT

ChAT (choline acetyltransferase) produces the protein choline acetyltransferase which produces the neurotransmitter acetylcholine.

Defects in this gene cause abnormal weakness of muscles (myasthenia),  associated with Alzheimer’s, depression, Rett syndrome and schizophrenia.


It's better to have this gene increased most of the time.
0 user want this gene increased, 0 users want it decreased

The Function of CHAT

Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.

Protein names

Recommended name:

Choline O-acetyltransferase

Alternative name(s):

CHOACTase
ChAT
Choline acetylase

Get a Grip on Your Health. Use SelfDecode to Interpret your Genome Today! GET INSTANT ACCESS

Top Gene-Substance Interactions

CHAT Interacts with These Diseases

Substances That Increase CHAT

Substances That Decrease CHAT

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical