The Function of CASP7

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

Protein names

Recommended name:

Caspase-7

Short name:

CMH-1

Alternative name(s):

CASP-7
Apoptotic protease Mch-3
ICE-like apoptotic protease 3
ICE-LAP3

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Top Gene-Substance Interactions

CASP7 Interacts with These Diseases

Substances That Increase CASP7

Substances That Decrease CASP7

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical