The Function of CASP12

Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF.

Protein names

Recommended name:

Inactive caspase-12

Short name:


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Top Gene-Substance Interactions

CASP12 Interacts with These Diseases

Substances That Increase CASP12

Substances That Decrease CASP12

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity