The Function of CA2

Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.

Protein names

Recommended name:

Carbonic anhydrase 2

Short name:


Alternative name(s):

Carbonate dehydratase II
Carbonic anhydrase C
Carbonic anhydrase II

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Top Gene-Substance Interactions

CA2 Interacts with These Diseases

Substances That Increase CA2

Substances That Decrease CA2

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity