Function

N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).

Protein names

Recommended name:

Amyloid beta A4 protein

Short name:

42

Alternative name(s):

ABPP
APPI
APP
Alzheimer disease amyloid protein
Amyloid precursor protein
Beta-amyloid precursor protein
Cerebral vascular amyloid peptide
CVAP
PreA4
Protease nexin-II
PN-II
S-APP-alpha
S-APP-beta
Beta-APP42
Beta-APP40
40
Amyloid intracellular domain 59
AICD-59
AID(59
Gamma-CTF(59
Amyloid intracellular domain 57
AICD-57
AID(57
Gamma-CTF(57
Amyloid intracellular domain 50
AICD-50
AID(50
Gamma-CTF(50

Get a Grip on Your Health. Use SelfDecode to Interpret your Genome Today! GET INSTANT ACCESS

Top Gene-Substance Interactions

Gene Interacts with Diseases

All Ways to Increase Gene

All Ways to Decrease Gene

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical