The Function of APOA1

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

Protein names

Recommended name:

Apolipoprotein A-I

Alternative name(s):

Apolipoprotein A1
Apolipoprotein A-I(1-242

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Top Gene-Substance Interactions

APOA1 Interacts with These Diseases

Substances That Increase APOA1

Substances That Decrease APOA1

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity