Summary of ADORA2A

This gene encodes proteins that respond to extracellular cues and activate intracellular signal transduction pathways. The proteins play an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep (R).

It is associated with inflammatory diseases and neurodegenerative disorders (R).

The Function of ADORA2A

Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

Protein names

Recommended name:

Adenosine receptor A2a

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Top Gene-Substance Interactions

ADORA2A Interacts with These Diseases

Substances That Increase ADORA2A

Substances That Decrease ADORA2A

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity