Summary of ACE

Converts angiotensin I to angiotensin II, which results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator.

ACE, or angiotensin-converting enzyme, increases the stress response, causing the release of adrenaline and noradrenaline (RefRef2). ACE increases the fight or flight nervous system, HPA axis (Ref), vasoconstriction, blood pressure, aldosterone, cortisol, and vasopressin (Ref). 

'Deletion' in the ACE gene can cause higher ACE and cause higher blood pressure, risk for stroke, hypertension, greater risk for heart attack, etc. 


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Protein names

Recommended name:

Angiotensin-converting enzyme

Short name:

ACE

Alternative name(s):

Dipeptidyl carboxypeptidase I
Kininase II
CD antigen CD143

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Top Gene-Substance Interactions

ACE Interacts with These Diseases

Substances That Increase ACE

Substances That Decrease ACE

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity

Technical