Converts angiotensin I to angiotensin II, which results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator.

ACE, or angiotensin-converting enzyme, increases the stress response, causing the release of adrenaline and noradrenaline (RefRef2). ACE increases the fight or flight nervous system, HPA axis (Ref), vasoconstriction, blood pressure, aldosterone, cortisol, and vasopressin (Ref). 

'Deletion' in the ACE gene can cause higher ACE and cause higher blood pressure, risk for stroke, hypertension, greater risk for heart attack, etc. 

It's better to have this gene decreased most of the time.

Protein names

Recommended name:

Angiotensin-converting enzyme

Short name:


Alternative name(s):

Dipeptidyl carboxypeptidase I
Kininase II
CD antigen CD143

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