Summary of ABCC2

The ABCC2 gene encodes a protein called multidrug resistance protein 2 (MRP2). It is involved in the transport of substances out of cells and is mostly found in the liver, kidneys, intestine, and placenta. MRP2 clears certain drugs from organs and tissues, playing a part in drug metabolism (R). 

Mutations in this gene can cause jaundice and cancer (R). 

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Protein names

Recommended name:

Canalicular multispecific organic anion transporter 1

Alternative name(s):

ATP-binding cassette sub-family C member 2
Canalicular multidrug resistance protein
Multidrug resistance-associated protein 2

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Top Gene-Substance Interactions

ABCC2 Interacts with These Diseases

Substances That Increase ABCC2

Substances That Decrease ABCC2

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity