Summary of SLC6A3

The SLC6A3 gene encodes a protein dopamine transporter, which transports dopamine into the cell. Dopamine plays a role in thought, motivation, behavior, and control of movement (R). 

Mutations of this gene are associated with autism and ADHD (R).

The Function of SLC6A3

Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.

Protein names

Recommended name:

Sodium-dependent dopamine transporter

Short name:


Alternative name(s):

DA transporter
Solute carrier family 6 member 3

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Top Gene-Substance Interactions

SLC6A3 Interacts with These Diseases

Substances That Increase SLC6A3

Substances That Decrease SLC6A3

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity