Summary

This gene encodes a cytokine that inhibits the production of pro-inflammatory cytokines and chemokines (R).

IL-13 is part of the Th2 immune arm.


Function

Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages.

Protein names

Recommended name:

Interleukin-13

Short name:

IL-13

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