Summary of HGF

This gene encodes a protein that helps regulate cell growth and movement. Mutations can cause hearing loss and deafness (R).

The Function of HGF

Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

Protein names

Recommended name:

Hepatocyte growth factor

Short name:


Alternative name(s):

Scatter factor

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Top Gene-Substance Interactions

HGF Interacts with These Diseases

Substances That Increase HGF

Substances That Decrease HGF

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity