Summary of CAT

The CAT gene encodes pieces (subunits) of an enzyme called catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. 

Catalase breaks down hydrogen peroxide (H2O2) molecules into oxygen (O2) and water (H2O) and thereby mitigates the toxic effects of hydrogen peroxide; high levels of catalase is toxic to cells (R, R). 

Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells.

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The Function of CAT

Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.

Protein names

Recommended name:


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Top Gene-Substance Interactions

CAT Interacts with These Diseases

Substances That Increase CAT

Substances That Decrease CAT

Advanced Summary

Conditions with Increased Gene Activity

Conditions with Decreased Gene Activity