Definition

A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. Quinolinic acid (QUIN) is a product of tryptophan metabolism that can act as an endogenous brain excitotoxin when released by activated macrophages. (Valle et. al, Brain 127:1047 (2004)) [HMDB]

Get a Grip on Your Health. Use SelfDecode to Interpret your Genome Today! GET INSTANT ACCESS

Top Gene Interactions

Related Pathways

Quinolinic Acid Interacts with Diseases

Quinolinic Acid Interacts with Genes