Compound Health Effects
- Metabolism: In the liver, L-tyrosine is involved in a number of biochemical reactions, including protein synthesis and oxidative catabolic reactions. L-tyrosine that is not metabolized in the liver is distributed via the systemic circulation to the various tissues of the body.
- Uses/Sources: Tyrosine is claimed to act as an effective antidepressant, however results are mixed. Tyrosine has also been claimed to reduce stress and combat narcolepsy and chronic fatigue, however these claims have been refuted by some studies.
- Route of Exposure: L-tyrosine is absorbed from the small intestine by a sodium-dependent active transport process.
- Toxicity: LD<sub>50</sub> (oral, rat) > 5110 mg/kg
Mechanism of Action
|Target Name||Mechanism of Action||References|
Tyrosine--tRNA ligase, cytoplasmic
Tyrosine--tRNA ligase, mitochondrial