Flavouring ingredient; dietary supplement, nutrient
Leucine (abbreviated as Leu or L) is a branched-chain л±-amino acid with the chemical formulaHO2CCH(NH2)CH2CH(CH3)2. Leucine is classified as a hydrophobic amino acid due to its aliphatic isobutyl side chain. It is encoded by six codons (UUA, UUG, CUU, CUC, CUA, and CUG) and is a major component of the subunits in ferritin, astacin, and other 'buffer' proteins. Leucine is an essential amino acid, meaning that the human body cannot synthesize it, and it therefore must be ingested. It is important for hemoglobin formation.
Indicated to assist in the prevention of the breakdown of muscle proteins that sometimes occur after trauma or severe stress.
Mechanism of Action
|Target Name||Mechanism of Action||References|
Proton-coupled amino acid transporter 1
Branched-chain-amino-acid aminotransferase, cytosolic
Phospholipase A-2-activating protein
Intestinal-type alkaline phosphatase
Leucine--tRNA ligase, cytoplasmic
Leucine carboxyl methyltransferase 1
Leucine carboxyl methyltransferase 2
Probable leucine--tRNA ligase, mitochondrial
Alkaline phosphatase, tissue-nonspecific isozyme
Branched-chain-amino-acid aminotransferase, mitochondrial