Definition
An oleanolic acid from GLYCYRRHIZA that has some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation.
Aglycone from licorice (Glycyrrhiza glabra) Glycyrrhetinic acid is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid, which was obtained from the herb liquorice. It is used in flavoring and it masks the bitter taste of drugs like aloe and quinine. (Wikipedia)
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Top Gene Interactions
Related Pathways
Glycyrrhetinic Acid Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Pulmonary Fibrosis | 19.95 | |
Heart failure | 18.94 | |
Cell Transformation, Neoplastic | 17.14 | |
Drug-Related Side Effects and Adverse Reactions | 16.93 | |
Neoplasms, Hormone-Dependent | 16.64 |
|
Psoriasis | 15.84 |
|
Disorders of Sex Development | 15.38 |
|
Polycystic ovary syndrome | 15.04 |
References/Inference Genes
|
Carcinoma, Non-Small-Cell Lung | 14.52 | |
Liver Cirrhosis, Experimental | 14.2 | |
Hypertension | 14.07 | |
Liver Cirrhosis | 13.49 |
References/Inference Genes
|
Drug-induced liver injury | 12.48 | |
Non-alcoholic fatty liver disease | 12.01 |
|
Endometrial neoplasm | 11.93 |
|
Necrosis | 11.85 | |
Thyroid carcinoma | 11.82 |
|
Breast carcinoma | 11.59 | |
Liver Neoplasms | 11.35 | |
Stomach Neoplasms | 11.33 |