Definition

A thioxanthine with effects similar to the phenothiazine antipsychotics.

Description

Chlorprothixene is only found in individuals that have used or taken this drug. It is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. Chlorprothixene blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.

Get a Grip on Your Health. Use SelfDecode to Interpret your Genome Today! GET INSTANT ACCESS

Top Gene Interactions

Related Pathways

General Information

Mechanism of Action

Chlorprothixene Interacts with Diseases

Chlorprothixene Interacts with Genes