- Metabolism: Hepatic (cytochrome P-450 system); some renal. Half Life: 1 to 4 hours
- Uses/Sources: For management of symptoms related to hay fever and other types of allergy and used to help bring up phlegm, thin secretions, and make a cough productive.
- Symptoms: Signs of overdose include wheezing, tightness in the chest, fever, itching, bad cough, blue skin color, fits, swelling of face, lips, tongue, or throat.
- Route of Exposure: Well absorbed in the digestive tract.
Mechanism of Action
|Target Name||Mechanism of Action||References|
|Histamine H1 receptor||Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.||