Definition

Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.

Description

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.

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General Information

Toxicity

Mechanism of Action

Astemizole Interacts with Diseases

Astemizole Interacts with Genes